Melanotan II
Melanocortin analogue
Melanotan II is a synthetic cyclic melanocortin analogue studied in pigmentation, melanocortin receptor pharmacology, appetite, autonomic responses, and sexual-function pathways.
For laboratory and research use only. Not for human or veterinary use.
Form
Lyophilized
Available strengths
10 mg
Research class
Neuroendocrine Receptor Signaling
Evidence grade
Level III
Limited or preliminary human evidence
Scientific overview
Melanotan II is a synthetic cyclic melanocortin analogue studied in pigmentation, melanocortin receptor pharmacology, appetite, autonomic responses, and sexual-function pathways.
Mechanism under investigation
Agonizes multiple melanocortin receptors, including MC1R and central melanocortin receptors, producing broad and nonselective signaling.
Research evidence summary
Limited human investigation with substantial safety concerns.
Level III, Limited human evidence
Key research limitations
The compound is not an approved tanning or wellness product. Commercial materials may have uncertain identity and purity.
Safety & toxicology context
Reported concerns include nausea, flushing, blood-pressure changes, priapism, pigment changes, sympathomimetic toxicity, and serious neurologic or dermatologic case reports.
Regulatory & development status
No FDA-approved Melanotan II drug product; FDA identifies significant safety concerns.
Supplied strictly for in-vitro and ex-vivo laboratory research. Not for human or veterinary administration, diagnostic, or therapeutic use. Import and regulatory compliance remain the responsibility of the receiving researcher.
Lot documentation
Every Cendrix lot ships with an HPLC purity chromatogram, mass-spectrometry identity confirmation, appearance and reconstitution observations, and endotoxin testing where applicable. Lot certificates are retrievable from the Quality page using the lot number printed on the vial.
Curated references
External searches link to PubMed, ClinicalTrials.gov, Google Scholar, and FDA records. Cendrix does not endorse interpretations published in third-party sources.
Editorial provenance
- Last scientific review
- June 2026
- Literature search through
- June 2026
- Regulatory review status
- Pending counsel approval
Persistent disclaimer
For laboratory research use only. Not for human or veterinary use, diagnosis, treatment, prevention, or personal experimentation. This content summarizes published research and is not medical advice.