Catalog
Experimental Neuropeptide Signaling · Evidence Level III

Semax

Synthetic ACTH-derived peptide

Semax is a synthetic peptide based on an ACTH fragment and studied in neuroprotection, cognition, ischemia models, neurotrophic signaling, and stress response.

For laboratory and research use only. Not for human or veterinary use.

Form

Lyophilized

Available strengths

10 mg

Research class

Experimental Neuropeptide Signaling

Evidence grade

Level III

Limited or preliminary human evidence

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Scientific overview

Semax is a synthetic peptide based on an ACTH fragment and studied in neuroprotection, cognition, ischemia models, neurotrophic signaling, and stress response.

02

Mechanism under investigation

Reported experimental effects include modulation of BDNF and related neurotrophic pathways, monoamine signaling, oxidative stress, and inflammatory gene expression.

03

Research evidence summary

Limited human evidence with substantial regional and preclinical literature.

Level III, Limited human evidence

04

Key research limitations

Study quality, independent replication, formulation standardization, and relevance to modern clinical practice vary considerably.

05

Safety & toxicology context

Long-term CNS, endocrine, immunogenicity, reproductive, and interaction risks are not well characterized.

06

Regulatory & development status

No FDA-approved drug product; FDA has identified safety-information gaps for compounded Semax.

Supplied strictly for in-vitro and ex-vivo laboratory research. Not for human or veterinary administration, diagnostic, or therapeutic use. Import and regulatory compliance remain the responsibility of the receiving researcher.

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Available research formats

  • Semax, 10 mgLyophilized
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Lot documentation

Every Cendrix lot ships with an HPLC purity chromatogram, mass-spectrometry identity confirmation, appearance and reconstitution observations, and endotoxin testing where applicable. Lot certificates are retrievable from the Quality page using the lot number printed on the vial.

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Curated references

External searches link to PubMed, ClinicalTrials.gov, Google Scholar, and FDA records. Cendrix does not endorse interpretations published in third-party sources.

Editorial provenance

Last scientific review
June 2026
Literature search through
June 2026
Regulatory review status
Pending counsel approval

Persistent disclaimer

For laboratory research use only. Not for human or veterinary use, diagnosis, treatment, prevention, or personal experimentation. This content summarizes published research and is not medical advice.