Semax
Synthetic ACTH-derived peptide
Semax is a synthetic peptide based on an ACTH fragment and studied in neuroprotection, cognition, ischemia models, neurotrophic signaling, and stress response.
For laboratory and research use only. Not for human or veterinary use.
Form
Lyophilized
Available strengths
10 mg
Research class
Experimental Neuropeptide Signaling
Evidence grade
Level III
Limited or preliminary human evidence
Scientific overview
Semax is a synthetic peptide based on an ACTH fragment and studied in neuroprotection, cognition, ischemia models, neurotrophic signaling, and stress response.
Mechanism under investigation
Reported experimental effects include modulation of BDNF and related neurotrophic pathways, monoamine signaling, oxidative stress, and inflammatory gene expression.
Research evidence summary
Limited human evidence with substantial regional and preclinical literature.
Level III, Limited human evidence
Key research limitations
Study quality, independent replication, formulation standardization, and relevance to modern clinical practice vary considerably.
Safety & toxicology context
Long-term CNS, endocrine, immunogenicity, reproductive, and interaction risks are not well characterized.
Regulatory & development status
No FDA-approved drug product; FDA has identified safety-information gaps for compounded Semax.
Supplied strictly for in-vitro and ex-vivo laboratory research. Not for human or veterinary administration, diagnostic, or therapeutic use. Import and regulatory compliance remain the responsibility of the receiving researcher.
Available research formats
- Semax, 10 mgLyophilized
Lot documentation
Every Cendrix lot ships with an HPLC purity chromatogram, mass-spectrometry identity confirmation, appearance and reconstitution observations, and endotoxin testing where applicable. Lot certificates are retrievable from the Quality page using the lot number printed on the vial.
Curated references
External searches link to PubMed, ClinicalTrials.gov, Google Scholar, and FDA records. Cendrix does not endorse interpretations published in third-party sources.
Editorial provenance
- Last scientific review
- June 2026
- Literature search through
- June 2026
- Regulatory review status
- Pending counsel approval
Persistent disclaimer
For laboratory research use only. Not for human or veterinary use, diagnosis, treatment, prevention, or personal experimentation. This content summarizes published research and is not medical advice.