MOTS-c

MOTS-c is a peptide encoded within mitochondrial 12S rRNA and studied in cellular stress responses, glucose metabolism, AMPK signaling, exercise biology, aging, and mitochondrial–nuclear communication.

Preclinical work suggests effects on AMPK-related pathways, folate and purine metabolism, and adaptive stress signaling, including nuclear translocation under cellular stress.

Predominantly preclinical with early human observational or exploratory work.

Level IV, Predominantly preclinical

Endogenous association studies and animal experiments do not establish the effects of administered synthetic MOTS-c in humans.

Human pharmacokinetics, immunogenicity, long-term safety, and off-target metabolic effects are not established.

No FDA-approved drug product; FDA has identified safety-information gaps for compounded MOTS-c.

Supplied strictly for in-vitro and ex-vivo laboratory research. Not for human or veterinary administration, diagnostic, or therapeutic use. Import and regulatory compliance remain the responsibility of the receiving researcher.

• MOTS-c, 10 mgLyophilized
• MOTS-c, 20 mgLyophilized

Every Cendrix lot ships with an HPLC purity chromatogram, mass-spectrometry identity confirmation, appearance and reconstitution observations, and endotoxin testing where applicable. Lot certificates are retrievable from the Quality page using the lot number printed on the vial.

External searches link to PubMed, ClinicalTrials.gov, Google Scholar, and FDA records. Cendrix does not endorse interpretations published in third-party sources.